ترجمه متن
سلام
من یه متن انگلیسی دارم که ازتون می خوام برام ترجمه کنید ولی چون زیاده 3 قسمت می کنم
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BACKGROUND AND PURPOSE: Diffusion-weighted images (DWIs) have been used to study various diseases, particularly since echo-planar techniques shorten examination time. Our hypothesis was that DWIs and tumor apparent diffusion coefficients (ADCs) could provide additional useful information in the diagnosis of patients with brain tumors.
METHODS: Using a 1.5-T MR unit, we examined 56 patients with histologically verified or clinically diagnosed brain tumors (17 gliomas, 21 metastatic tumors, and 18 meningiomas). We determined ADC values and signal intensities on DWIs both in the solid portion of the tumor and in the peritumoral, hyperintense areas on T2-weighted images. We also evaluated the correlation between ADC values and tumor cellularity in both gliomas and meningiomas.
RESULTS: The ADCs of low-grade (grade II) astrocytomas were significantly higher (P = .0004) than those of other tumors. Among astrocytic tumors, ADCs were higher in grade II astrocytomas (1.14 ± 0.18) than in glioblastomas (0.82 ± 0.13). ADCs and DWIs were not useful in determining the presence of peritumoral neoplastic cell infiltration. The ADC values correlated with tumor cellularity for both astrocytic tumors (r = -.77) and meningiomas (r = -.67).
CONCLUSION: The ADC may predict the degree of malignancy of astrocytic tumors, although there is some overlap between ADCs of grade II astrocytomas and glioblastomas.
Introduction
MR diffusion imaging has been used to study various diseases and the normal brain (1–10). The development of techniques capable of accurately depicting tumor grades in vivo is important for determination of the most appropriate treatment for glioma. An unfortunate choice of biopsy site or insufficiently large samples may result in an incorrect histologic diagnosis. In malignant gliomas, peritumoral edema, which can be depicted with either CT or MR imaging, often has been reported to have infiltrating neoplastic cells (11). Therefore, the tumor border is still inaccurately depicted even with imaging techniques. Because our initial observations of astrocytic tumors revealed a relatively good correlation between apparent diffusion coefficient (ADC) and tumor cellularity, we expanded our study to include brain tumors metastasized from elsewhere and meningiomas, both of which commonly have peritumoral edema. Our hypothesis was that diffusion-weighted images (DWIs) and tumor ADCs could provide additional useful information in the diagnosis of patients with brain tumors, such as tumor malignancy, peritumoral infiltration, and the type of meningioma
Results :
ADCs of Tumor and Peritumoral, Hyperintense Areas on T2-weighted Images
The ADCs of the tumors are shown in Figure 6. They ranged from 0.65 to 1.06 x 10-3 mm2/s (mean 0.82 ± 0.13 10-3 mm2/s) in nine patients with glioblastoma, from 0.88 to 1.41 x 10-3 mm2/s (1.14 ± 0.18 x 10-3 mm2/s) in eight patients with grade II astrocytoma, from 0.35 to 1.37 (0.79 ± 0.23 x 10-3 mm2/s) in 21 patients with metastatic tumor, and from 0.51 to 1.08 (0.78 ± 0.17 x 10-3 mm2/s) in 18 patients with meningioma. Among patients with astrocytic tumors, those with glioblastoma had lower ADC values than those with grade II astrocytoma (P = .0008). The ADC did not differ significantly between patients with glioblastomas versus metastatic tumors. Patients with meningiomas had a wide range of ADCs: from 0.51 to 1.11 x 10-3 mm2/s (0.80 ± 0.22 x 10-3 mm2/s) in eight patients with meningothelial meningioma, and 0.62 to 0.88 x 10-3 mm2/s (0.74 ± 0.08 x 10-3 mm2/s) in eight patients with fibrous meningioma, to 0.66 x 10-3 mm2/s and 1.04 x 10-3 mm2/s in 2 patients with transitional meningioma. For patients with meningioma, tumor histology (meningothelial meningioma, fibrous meningioma or transitional meningioma) did not
correlate significantly with ADC
لغتهای پزشکی و نامفهوم مشل ADC یا DWI به مون صورت انگلیسی بمونه
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نوشته شده توسط phoenixtranslator
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