Tuesday, October 7, 2008
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Ibuprofen 'cuts risk of breast cancer by fifth'
Taking common painkillers can cut the risk of breast cancer by up to a fifth, a study has found.
Aspirin reduced the danger by 13 per cent, while ibuprofen cut the risk by 21 per cent, a review of 2.7million cases has found.
Both are non-steroidal anti-inflammatory drugs (NSAIDs) which inhibit two enzymes in the body linked to cancer proliferation
Cox 1 and 2 enzymes are thought to affect the creation of blood vessels that feed tumours, tissue invasion by cancer cells, and the responsiveness of our immune system.
'The results are encouraging and may help us better understand the importance of inflammation in the pathology of the disease,' said Dr Mahyar Etminan from the University of British Columbia, which led the research.
The findings were published in the US Journal of the National Cancer Institute after data from more than 38 studies in five countries were brought together.
However, previous studies looking at whether NSAIDs can protect against breast cancer have produced conflicting results. A 2005 study of 100,000 US women found ibuprofen instead increased breast cancer risks.
But, by combining results from a number of investigations, it is thought a clearer picture has emerged.
Charity Cancer Research UK was optimistic about the findings but warned of the dangers of regularly taking painkillers.
'More research is needed,' said the charity's Dr Jodie Moffat